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nput-output (I-O) analysis is an important technique used to estimate how changes in one sector of the economy affect employment, wages, and overall production in other sectors. An economist named Wassily Leontief developed the technique decades ago, receiving the 1973 Nobel Memorial Prize in Economic Sciences for doing so. Today, analysts customize national I-O “accounts” produced by the U.S. Bureau of Economic Analysis in order to study regional (sub-national) effects. These accounts describe how industries, households, and government exchange goods and services, and regional models, in turn, use this information to simulate the magnitude, direction, and timing of economic impacts.